132427-78-2Relevant articles and documents
Antiinflammatory phospholipase-A2 inhibitors. I.
Wilkerson,DeLucca,Galbraith,Gans,Harris,Jaffee,Kerr
, p. 667 - 676 (2007/10/02)
A novel series of dehydroabietylamine derivatives has been synthesized and shown to be inhibitors of phospholipase-A2 (PLA2). These compounds exhibit in vivo antiinflammatory activity in the rat carrageenan paw edema assay and support the concept of PLA2 inhibition as an approach to the discovery of novel antiinflammatories.