132431-08-4Relevant articles and documents
Boron trifluoride promoted cleavage of benzyl carbamates
Subhas Bose,Thurston, David E.
, p. 6903 - 6906 (2007/10/02)
A new efficient method for the cleavage of benzyl carbamates (CBZ protective groups) is described that involves a hard acid (BF3·OEt2) - soft nucleophile (EtSH) system. Unlike other available methods, this combination avoids the reduction of olefins, acetylenes, imines, halides and nitro groups, or the possibility of carboxylic ester hydrolysis.