132431-11-9

Basic information

• Product Name: 1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 2-Methyl 1-(phenylMethyl) ester, (R)-
• Synonyms: 1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 2-Methyl 1-(phenylMethyl) ester, (R)-;(R)-1-benzyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate
• CAS NO: 132431-11-9
• Molecular Formula: C₁₄H₁₅NO₅
• Molecular Weight: 277.2726
• Mol File: 132431-11-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 422.1±45.0 °C(Predicted)
• Appearance: /
• Density: 1.306±0.06 g/cm3(Predicted)
• PKA: -3.91±0.40(Predicted)
• CAS DataBase Reference: 1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 2-Methyl 1-(phenylMethyl) ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 2-Methyl 1-(phenylMethyl) ester, (R)-(132431-11-9)
• EPA Substance Registry System: 1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 2-Methyl 1-(phenylMethyl) ester, (R)-(132431-11-9)

Safety Data

• Hazardous Substances Data: 132431-11-9(Hazardous Substances Data)

Usage

General Description

The chemical "1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 2-Methyl 1-(phenylMethyl) ester, (R)-" is a complex organic compound that is typically found in a solid state. It belongs to the esters class of chemical compounds, which are characterized by a carbon-oxygen double bond. Due to the presence of its phenyl group, it may have aromatic characteristics. The "(R)-" in its name indicates it has a specific orientation in space; in this case, it is a right-handed or rectus configuration. Its various chemical groups give it potential reactivity with various other substances, making it of interest in the field of organic chemistry.

Upstream product

• 92246-88-3 N-carbobenzyloxy-trans-4-hydroxy-L-proline methyl ester 
• 79-37-8 oxalyl dichloride 
• 67-68-5 dimethyl sulfoxide 
• 7087-68-5 N-ethyl-N,N-diisopropylamine 
• 155075-23-3 (2R,4R)-1-benzyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 
• 132431-08-4 4-Oxo-pyrrolidine-2-carboxylic acid methyl ester 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 132431-08-4 4-Oxo-pyrrolidine-2-carboxylic acid methyl ester 
• 1418177-80-6 (2R,4S)-1-benzyloxycarbonyl-4-hydroxy-4-(4-methoxyphenyl)pyrrolidine-2-carboxylic acid 
• 1418177-77-1 C₁₂H₁₅NO₄ 
• 1418177-74-8 methyl (2R,4S)-1-benzyloxycarbonyl-4-hydroxy-4-(4-methoxyphenyl)pyrrolidine-2-carboxylate 
• 1610036-83-3 (1S,2R,5R)-3-benzyl 2-methyl 6-oxa-3-azabicyclo[3.1.0]hexane-2,3-dicarboxylate 
• 1610036-84-4 (1R,2R,5S)-3-benzyl 2-methyl 6-oxa-3-azabicyclo[3.1.0]hexane-2,3-dicarboxylate 
• 1610036-31-1 (R)-7-benzyl 8-methyl 1,4-dioxa-7-azaspiro[4.4]nonane-7,8-dicarboxylate 
• 1610036-82-2 (R)-1-benzyl 2-methyl 4-(((trifluoromethyl)sulfonyl)oxy)-1H-pyrrole-1,2(2H,5H)-dicarboxylate 
• 1351851-12-1 C₄₃H₅₄N₈O₇ 
• 1374356-74-7 C₃₉H₄₈N₆O₅ 

Relevant articles and documents

PYRROLIDINE GPR40 MODULATORS

The present invention provides compounds of Formula (I): or a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, or a solvate thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.

PYRROLIDINE GPR40 MODULATORS

The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.

HEPATITIS C VIRUS INHIBITORS

Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.