132434-56-1Relevant articles and documents
MACROCYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS
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Page/Page column 75, (2009/12/05)
The present invention relates to macrocyclic compounds of Formula I: or pharmaceutically acceptable salts thereof or quaternary ammonium salts thereof wherein constituent members are provided hereinwith, as well as their compositions and methods of use, w
Synthesis and antifungal activity of 1,3-bis(4-methyl/4-bromo/3-nitrophenyl) propan-1,3-diones and their 2 analogs
Suman, Mrs.,Singh, Rajvir,Malik, M. S.,Kathpal, T. S.,Malik, O. P.
, p. 743 - 746 (2007/10/03)
The reaction of substituted acetophenones (1-3) with 4-methyl-, 4-bromo- or 3-nitrobenzaldehyde (4-6) in ethanolic NaOH gives the correponding 1,3-bis(4-methyl/4-bromo/3-nitrophenyl)-2-propen-1-ones (7-9) in good yields, which on bromination yield substit
Photochemical Reactions of Phthalamido Derivatives of 1,3-Diphenyl-2-propen-1-one and Its Analogs
Kudryavtsev, V. V.,Nosova, G. I.,Solovskaya, N. A.,Dobrodumov, A. V.,Rtishchev, N. I.,Frolov, A. N.
, p. 513 - 519 (2007/10/03)
According to luminescence spectral data, the singlet excited state of 1,4-bis(3-aryl-3-oxo-1-propenyl)benzene derivatives is of ?, ?* type, whereas those of 1,3-diaryl-2-propen-1-ones and 1,4-bis(3-phenyl-2-propenoyl)benzene are of n, ?* type.When irradiated in solutions in alcohol, CDCl3, or tetrahydrofuran, these compounds undergo photochemical isomerization and cacloaddition and react with oxygen.As follows from the quantum yields, photoisomerization is the predominant process for 1,3-diaryl-2-propen-1-ones and 1,4-bis(3-phenyl-2-propenoyl)benzene, whereas for 1,4-bis(3-aryl-3-oxo-1-propenyl)benzenes the main route is cycloaddition; the efficiency of these photochemical conversions decreases in going from the two first compounds to the latter.Presumably, one of the reasons is the different reactive excited states.