132449-46-8 Usage
General Description
Lesopitron is a chemical compound that belongs to the class of serotonin receptor ligands and is typically used as an anxiolytic agent. It acts as a selective serotonin 5-HT1A receptor partial agonist, meaning that it binds to and activates these receptors in the brain, resulting in anxiolytic and antidepressant effects. Lesopitron has been studied for its potential use in the treatment of anxiety disorders, depression, and other related conditions, although its development has been discontinued in some countries due to concerns about its safety and efficacy. Nonetheless, research on the pharmacological properties and potential therapeutic uses of lesopitron and related compounds continues, as scientists seek to develop effective treatments for mental health disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 132449-46-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,4,4 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 132449-46:
(8*1)+(7*3)+(6*2)+(5*4)+(4*4)+(3*9)+(2*4)+(1*6)=118
118 % 10 = 8
So 132449-46-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H21ClN6/c16-14-12-19-22(13-14)7-2-1-6-20-8-10-21(11-9-20)15-17-4-3-5-18-15/h3-5,12-13H,1-2,6-11H2
132449-46-8Relevant articles and documents
Process for the preparation of 2-(4-[4-(4-chloro-1-pyrazolyl)butyl]-1-piperazinyl)pyrimidine (Lesopitron)
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, (2008/06/13)
The present invention relates to a process for the preparation of 2-{4-[4-(4-chloro-1-pyrazolyl)buty1]-1-piperazinyl}pyrimidine (Lesopitron) of formula I: STR1 characterized in that the reaction between 2-(1-piperazinyl)pyrimidine, 4-chloropyrazole and the carbon chain of formula (III) STR2 in which X and Y, which may be identical or different, represent a suitable leaving group, is carried out in a single step in a suitable solvent.
