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132462-15-8

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132462-15-8 Usage

General Description

2(3H)-Thiophenone, dihydro-3-methyl-3-(1-methylethyl)-(9CI) is a chemical compound with the molecular formula C9H14OS. It is a colorless to pale yellow liquid with a strong odor. 2(3H)-Thiophenone,dihydro-3-methyl-3-(1-methylethyl)-(9CI) is commonly used as a flavoring ingredient in the food and beverage industry due to its fruity and floral aroma. It is also used as a fragrance ingredient in perfumes and personal care products. Additionally, it has potential applications in the pharmaceutical industry as a precursor for the synthesis of various pharmaceutical compounds. However, it is important to handle this chemical with care as it can be irritating to the skin, eyes, and respiratory system.

Check Digit Verification of cas no

The CAS Registry Mumber 132462-15-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,4,6 and 2 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 132462-15:
(8*1)+(7*3)+(6*2)+(5*4)+(4*6)+(3*2)+(2*1)+(1*5)=98
98 % 10 = 8
So 132462-15-8 is a valid CAS Registry Number.

132462-15-8Downstream Products

132462-15-8Relevant articles and documents

Synthesis and structure-activity studies of alkyl-substituted γ-butyrolactones and γ-thiobutyrolactones: Ligands for the picrotoxin receptor

Canney,Holland,Levine,McKeon,Ferrendelli,Covey

, p. 1460 - 1467 (1991)

A series of γ-butyrolactones and γ-thiobutyrolactones possessing a variety of alkyl groups and alkyl-substitution patterns was prepared and evaluated for anticonvulsant and convulsant activity. Behavioral studies performed on these compounds suggest that maximal anticonvulsant activity (against maximal electroshock and pentylenetetrazol) results when three or four carbon atoms are present at the α-position. For convulsant potency, a similar dependence on the size of the alkyl chain at the β-position was observed. Additional γ-dimethyl groups were found to increase the convulsant potency of a β-substituted compound and to cause an an α-substituted anticonvulsant to become a convulsant. In general, sulfur for oxygen heteroatom substitution in the α-substituted lactones resulted in improved anticonvulsant potency and spectrum of activity. Binding of these compounds to the picrotoxin site of the GABA receptor complex was demonstrated with a [35S]-tert-butylbicyclophosphorothionate radioligand binding assay. Measurements of brain concentrations for selected compounds supports a hypothesis that correlates binding to the picrotoxin site with the pharmacological effects of these compounds.

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