132465-11-3

Basic information

• Product Name: CDC
• Synonyms: CINNAMYL-3,4-DIHYDROXY-ALPHA-CYANOCINNAMATE;CDC;(E,Z)-2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenoic acid 3-phenyl-2-propenyl ester;Cinnamyl 3,4-dihydroxy-alpha-cyanocinnamate CDC;1-Cyclohexy1-3-(3-dimethylamino proply)carbodilimide methiodide
• CAS NO: 132465-11-3
• Molecular Formula: C₁₉H₁₅NO₄
• Molecular Weight: 321.33
• Mol File: 132465-11-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 583.9 °C at 760 mmHg
• Flash Point: 307 °C
• Appearance: light yellow to yellow/
• Density: 1.326 g/cm³
• Storage Temp.: room temp
• Solubility: DMSO: ≥15mg/mL
• CAS DataBase Reference: CDC(CAS DataBase Reference)
• NIST Chemistry Reference: CDC(132465-11-3)
• EPA Substance Registry System: CDC(132465-11-3)

Safety Data

• Hazard Codes: Xi,N
• Statements: 43-50/53
• Safety Statements: 36/37-60-61
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• HazardClass: 9
• Hazardous Substances Data: 132465-11-3(Hazardous Substances Data)

Usage

Uses

CDC is an inhibitor of 5-LO, 12-LO, and 15-LO.

Synthetic route

(E)-3-phenylallyl α-cyanoacetate (132465-21-5) + 3,4-dihydroxybenzaldehyde (139-85-5) → cinnamyl 3,4-dihydroxyl-α-cyanocinnamate (132465-11-3)

Conditions	Yield
With piperidine In N,N-dimethyl-formamide; benzene Heating;

Upstream product

• 132465-21-5 (E)-3-phenylallyl α-cyanoacetate 
• 139-85-5 3,4-dihydroxybenzaldehyde 

Relevant articles and documents

Novel Caffeic Acid Derivatives: Extremely Potent Inhibitors of 12-Lipoxygenase

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