132496-77-6

Basic information

• Product Name: Methyl 3-chloro 4,5-dihydroxy benzoate
• Synonyms: Methyl 3-chloro 4,5-dihydroxy benzoate
• CAS NO: 132496-77-6
• Molecular Formula: C8H7ClO4
• Molecular Weight: 202.59178
• EINECS: -0
• Mol File: 132496-77-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 360.4±37.0 °C(Predicted)
• Appearance: /
• Density: 1.488±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 6.73±0.23(Predicted)
• CAS DataBase Reference: Methyl 3-chloro 4,5-dihydroxy benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-chloro 4,5-dihydroxy benzoate(132496-77-6)
• EPA Substance Registry System: Methyl 3-chloro 4,5-dihydroxy benzoate(132496-77-6)

Safety Data

• Hazardous Substances Data: 132496-77-6(Hazardous Substances Data)

Usage

General Description

Methyl 3-chloro 4,5-dihydroxy benzoate is a compound belonging to the class of organic chemicals known as benzoates. It is a derivative of benzoic acid and contains a methyl group, a chlorine atom, and two hydroxyl groups on its aromatic ring. Methyl 3-chloro 4,5-dihydroxy benzoate has potential applications in the pharmaceutical and agrochemical industries due to its biological activity. It may also be used as a building block in the synthesis of various organic compounds. Its specific properties and uses may vary depending on the intended application.

Upstream product

• 67-56-1 methanol 
• 20624-87-7 3-chloro-4,5-dimethoxybenzoic acid 
• 87932-49-8 3-chloro-4,5-dihydroxybenzoic acid 
• 62936-23-6 3-chloro-4-hydroxy-5-methoxybenzoic acid 
• 393-06-6 4-amino-2-(trifluoromethyl)benzoic acid 
• 2150-43-8 3,4-dihydroxybenzoic acid methyl ester 

Downstream Products

• 1272528-34-3 3-chloro-4,5-bis(cyclopentyloxy)benzoic acid 
• 1272528-35-4 methyl 4-[3-chloro-4,5-bis(cyclopentyloxy)benzamido]benzoate 
• 1272527-22-6 4-[3-chloro-4,5-bis(cyclopentyloxy)benzamido]benzoic acid 
• 1272528-43-4 methyl 4-(3,4-di-tert-butoxy-5-chlorobenzamido)benzoate 
• 1272527-26-0 4-(3,4-di-tert-butoxy-5-chlorobenzamido)benzoic acid 
• 1272528-46-7 methyl 3-chloro-4-benzyloxy-5-isopropoxybenzoate 
• 1272528-47-8 methyl 3-chloro-4-hydroxy-5-isopropoxybenzoate 
• 1272527-61-3 4-(3-chloro-4-ethoxy-5-isopropoxybenzamido)-2-methylbenzoic acid 
• 1272527-28-2 4-(3-chloro-4,5-diisopropoxybenzamido)benzoic acid 
• 1272527-71-5 4-(3-chloro-4,5-di(cyclobutyloxy)benzamido)benzoic acid 
• 1272527-29-3 4-(3-chloro-4,5-diisopropoxybenzamido)-2-methylbenzoic acid 
• 1272527-27-1 4-(3,4-di-tert-butoxy-5-chlorobenzamido)-2-methylbenzoic acid 

Relevant articles and documents

Cefiderocol (S-649266), A new siderophore cephalosporin exhibiting potent activities against Pseudomonas aeruginosa and other gram-negative pathogens including multi-drug resistant bacteria: Structure activity relationship

The structure-activity relationship (SAR) for a novel series of catechol conjugated siderophore cephalosporins is described with their in vitro activities against multi-drug resistant Gram-negative pathogens including Pseudomonas aeruginosa, Acinetobacter baumannii, Stenotrophomonas maltophilia and Enterobacteriaceae. Cefiderocol (3) was one of the best molecules which displayed well-balanced and potent activities against multi-drug resistant Gram-negative pathogens including carbapenem resistant bacteria among the prepared compounds with the modified C-7 side chain and the modified C-3 side chain. Cefiderocol (3) is a highly promising parenteral cephalosporin for the treatment of multi-drug resistant Gram-negative infection.

CEPHEM COMPOUND HAVING CATECHOL GROUP

A compound of the formula: wherein X is -N=, -CH=, or the like; W is -CH2- or the like; U is -S- or the like; R1 and R2 are each independently hydrogen, halogen, optionally substituted lower alkyl, or the like; R3/su

THERAPEUTIC ARYL-AM I DO-ARYL COMPOUNDS AND THEIR USE

The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-amido-aryl compounds of the following formula (for convenience, collectively referred to herein as "AAA compounds"), which, inter alia, a