132555-22-7

Basic information

• Product Name: 3-(2-hydroxy-5-methylphenyl)pyridine
• Synonyms: 3-(2-hydroxy-5-methylphenyl)pyridine
• CAS NO: 132555-22-7
• Molecular Weight: 185.225
• Mol File: 132555-22-7.mol

Chemical Properties

• CAS DataBase Reference: 3-(2-hydroxy-5-methylphenyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-hydroxy-5-methylphenyl)pyridine(132555-22-7)
• EPA Substance Registry System: 3-(2-hydroxy-5-methylphenyl)pyridine(132555-22-7)

Safety Data

• Hazardous Substances Data: 132555-22-7(Hazardous Substances Data)

Upstream product

• 106-44-5 p-cresol 
• 132555-20-5 (Z)-tert-Butyl 3-pyridylazo sulfide 
• 694-59-7 pyridine N-oxide 
• 262373-15-9 4-methyl-2-(trimethylsilyl)phenyl trifluoromethanesulfonate 

Relevant articles and documents

Regioselective synthesis of 3-(2-hydroxyaryl)pyridines via arynes and pyridine N-oxides

A variety of substituted 3-(2-hydroxyphenyl)pyridines have been prepared regioselectively by a transition-metal-free, mild, one-step route, which involves the reaction of pyridine N-oxides with silylaryl triflates in the presence of CsF in acetonitrile at

SRN1C-arylation of potassium aryloxides by arylazo phenyl or tert- butyl sulfides in DMSO

Aryloxide ions (Ar′O-) behave as C-nucleophiles towards diazosulfides (ArN = NSR; R = Ph, But) leading to imsymmetrical hydroxybiaryls (ArAr′OH) via C-C coupling. The reaction is particularly suited for the synthesis of terms which contain electron-withdrawing groups on the Ar moiety. The SRN1 mechanism is proposed on the grounds of experimental evidences.