13256-07-0 Usage
Chemical Properties
Yellow Viscous Liquid
Uses
A potent esophageal carcinogen
Safety Profile
Poison by ingestion,
subcutaneous, and intraperitoneal routes.
Suspected carcinogen with experimental
carcinogenic, neoplas tigenic, and
tumorigenic data. Mutation data reported.
When heated to decomposition it emits
toxic NO,. See also NITROSAMINES and
N-NITROSO COMPOUNDS.
Check Digit Verification of cas no
The CAS Registry Mumber 13256-07-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,2,5 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 13256-07:
(7*1)+(6*3)+(5*2)+(4*5)+(3*6)+(2*0)+(1*7)=80
80 % 10 = 0
So 13256-07-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H14N2O/c1-3-4-5-6-8(2)7-9/h3-6H2,1-2H3
13256-07-0Relevant articles and documents
β-KETONITROSAMINES. SYNTHETIC EQUIVALENTS OF α-METHYLENE ALKYLAMINO ANIONS (-CH2NHR).
Saavedra, Joseph E.,Farnsworth, David W.,Farrelly, James G.
, p. 1147 - 1156 (2007/10/02)
β-Ketonitrosamines are important in the study of nitrosamine metabolism, carcinogenesis and in vivo alkylation.The enhanced acidity of protons at the α-carbon, as well as the ease of fragmentation of the title compounds establishes them as synthetic equivalents of α-methylene alkylamino anions (-CH2NHR).Anion formation is carried out with powdered sodium hydroxide - sodium carbonate in DMF or THF at 25 deg C.Reaction with an alkyl halide gives a good yield of the alkylated product.Retro-Claisen cleavage in aqueous basic media gives the corresponding dialkyl - nitrosamine or, with D2O, the deuterated analog.
