13256-12-7

Usage

Uses

Used in Dye Production:
NNDINITROSONNDIMETHYLETHYLENEDIAMINE is used as a chemical intermediate for the synthesis of various dyes. Its reactivity allows for the creation of a range of colorants used in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, NNDINITROSONNDIMETHYLETHYLENEDIAMINE is used as a building block for the development of certain medications. Its chemical properties make it a valuable component in the synthesis of specific drug compounds.
Safety Precautions:
When working with NNDINITROSONNDIMETHYLETHYLENEDIAMINE, it is crucial to adhere to proper safety procedures. This includes the use of protective equipment such as gloves, goggles, and masks to prevent skin contact, eye exposure, and inhalation. Additionally, handling this chemical in a well-ventilated area or under a fume hood can further reduce the risk of respiratory issues.

InChI:InChI=1/C4H10N4O2/c1-7(5-9)3-4-8(2)6-10/h3-4H2,1-2H3

Upstream product

• 62-75-9 N-Nitrosodimethylamine 
• 110-70-3 N,N`-dimethylethylenediamine 
• 23834-30-2 1-dimethylamino-2-methylnitrosaminoethane 
• 110-18-9 N,N,N,N,-tetramethylethylenediamine 
• 49666-38-8 1,4-dimethyl-1,4,5,6-tetrahydro-[1,2,3,4]tetrazine 2-oxide 

Relevant academic research and scientific papers

Nitric oxide reactivity of copper(ii) complexes of bidentate amine ligands: Effect of substitution on ligand nitrosation

Three copper(ii) complexes with bidentate ligands L1, L 2 and L3 [L1, N,N/- dimethylethylenediamine; L2, N,N/-diethylethylenediamine and L3, N,N/-diisobutylethylenediamine], respectively, were synthesized as their perchlorate salts. The single crystal structures for all the complexes were determined. The nitric oxide reactivity of the complexes was studied in acetonitrile solvent. The formation of thermally unstable [CuII-NO] intermediate on reaction of the complexes with nitric oxide in acetonitrile solution was observed prior to the reduction of copper(ii) centres to copper(i). The reduction was found to result with a simultaneous mono- and di-nitrosation at the secondary amine sites of the ligand. All the nitrosation products were isolated and characterized. The ratio of the yield of mono- and di-nitrosation product was found to be dependent on the N-substitution present in the ligand framework.

Nitrolysis of Tertiary Amines: Piperidines, Piperazines, Bisdimethylaminoalkanes, and Functionalized Methyldialkylamines

Preparative amounts of mono- and di-nitrosamines were obtained from aliphatic cyclic and acyclic tertiary monamines and diamines by treatment with dinitrogen tetraoxide in carbon tetrachloride at 0 - 45 deg C.N-Methyl- and N-ethyl-piperidines (1) and (2) gave N-nitrosopiperidine (15), but N-isopropyl- and N-t-butyl-piperidines (3) and (4) did not.N-Methyl-, N-ethyl-, N-isopropyl- and N-t-butyl-N'-methylpiperazines (5) - (8) gave N,N'-dinitrosopiperazine (22) (in 90 percent, 81 percent, 55 percent, and 8 percent yields, respectively) and the diamine (8) also gave N-t-butyl-N'-dinitrosopiperazine (23) (45 percent).The N'-nitroso and the N'-nitro derivatives of N-methylpiperazine were similarly converted into N,N'-dinitroso- and N-nitroso-N'-nitropiperazines (22) (45 percent) and (30) (53 percent).Bisdimethylaminoalkanes (Me2N)2(CH2)n (10) - (14) gave bismethylnitrosaminoalkanes 2(CH2)n (24) - (27) and dimethylnitrosamine (28): n=1 (0 percent, 90 percent); n=2 (68 percent, 0 percent); n=3 (48 percent, 43 percent); n=4 (41 percent, 38 percent); n=6 (58 percent, 35 percent). β-Dimethylaminopropionitrile (18), 1-methylnitrosamino-2-dimethylaminoethane (17), and α-dimethylaminoacetic acid (19) gave the corresponding nitrosoamines by replacement of an N-methyl group.