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Urea, N-(4-methylphenyl)-N'-3-pyridinyl-, also known as 1-(4-methylphenyl)-3-(3-pyridinyl)urea or 4-methyl-N-(3-pyridinyl)phenylurea, is an organic compound with the chemical formula C13H13N3O. It is a derivative of urea, featuring a 4-methylphenyl group attached to the nitrogen atom and a 3-pyridinyl group attached to the other nitrogen atom. Urea, N-(4-methylphenyl)-N'-3-pyridinyl- is a white crystalline solid and is used as a chemical intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure allows it to form hydrogen bonds and interact with biological targets, making it a valuable component in the development of new drugs and pesticides.

13256-76-3

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13256-76-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 13256-76-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,2,5 and 6 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 13256-76:
(7*1)+(6*3)+(5*2)+(4*5)+(3*6)+(2*7)+(1*6)=93
93 % 10 = 3
So 13256-76-3 is a valid CAS Registry Number.

13256-76-3Relevant academic research and scientific papers

A modular, self-assembled, separated ion pair binding system

Turner, David R.,Spencer, Elinor C.,Howard, Judith A. K.,Tocher, Derek A.,Steed, Jonathan W.

, p. 1352 - 1353 (2004)

Assembly of a silver(I) complex of a simple pyridyl ligand containing a urea derivative is templated by nitrate; analogous complexes of Ag 2SO4 and AgCF3SO3 exhibit radically different geometries.

USE OF PYRIDINE UREA COMPOUND HAVING SNAIL-KILLING ACTIVITY

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Paragraph 0068-0070; 0086, (2021/01/29)

The present invention relates to use of a pyridine urea compound having snail-killing activities, and relates to a method for preparing the pyridine urea compound. In particular, the present invention discloses a compound having the structure as shown in formula (I), an optical isomer thereof, a racemate thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof, the compound having a significant killing effect on various snails as parasitic disease vectors and low toxicity to non-target organism fish.

Novel synthesis of ureas: Application of t-butylureas

Ito, Ai,Muratake, Hideaki,Shudo, Koichi

experimental part, p. 82 - 86 (2010/04/05)

Otherwise inaccessible tropolonylureas were prepared by reaction of t-butylurea with appropriate amines, with elimination of t-butylamine. This method is also generally applicable for urea synthesis.

Model studies on a synthetically facile series of N-substituted phenyl-N'-pyridin-3-yl ureas leading to 1-(3-pyridylcarbamoyl) indolines that are potent and selective 5-HT(2C/2B) receptor antagonists

Bromidge, Steven M.,Dabbs, Steven,Davies, David T.,Davies, Susannah,Duckworth, D.Malcolm,Forbes, Ian T.,Gadre, Angela,Ham, Peter,Jones, Graham E.,King, Frank D.,Saunders, Damian V.,Thewlis, Kevin M.,Vyas, Deepa,Blackburn, Thomas P.,Holland, Vicky,Kennett, Guy A.,Riley, Graham J.,Wood, Martyn D.

, p. 2767 - 2773 (2007/10/03)

A model series of 5-HT(2C) antagonists have been prepared by rapid parallel synthesis. These N-substituted phenyl-N'-pyridin-3-yl ureas were found to have a range of 5-HT(2C) receptor affinities and selectivities over the closely related 5-HT(2A) receptor. Extrapolation of simple SAR, derived from this set of compounds, to the more active but synthetically more complex 1-(3-pyridyl-carbamoyl)indoline series allowed us to target optimal substitution patterns and identify potent and selective 5-HT(2C/2B) antagonists. Copyright (C) 1999 Elsevier Science Ltd.

Heteroacyl Azides as Acylating Agents for Aromatic or Heteroatomic Amines (1)

Stanovnik, B.,Tisler, M.,Golob, V.,Hvala, I.,Nikolic, O.

, p. 733 - 736 (2007/10/02)

The possibility of formation of substituted heterocyclic amides from heteroacyl azides and aromatic or heteroatomic amines was investigated.Although acylation proceeded in some cases under mild reaction conditions, formation of N,N'-disubstituted ureas was the main process at elevated temperatures.

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