1325694-75-4Relevant academic research and scientific papers
Synthesis of an aryloxy oxo pyrimidinone library that displays ALK-selective inhibition
Slavish, P. Jake,Price, Jeanine E.,Jiang, Qin,Cui, Xiaoli,Morris, Stephan W.,Webb, Thomas R.
, p. 4592 - 4596 (2011)
We report the synthesis of a pyrimidinone library that targets anaplastic lymphoma kinase (ALK), an oncogenic receptor tyrosine kinase. This library was generated in three steps from a versatile commercially available starting material. Some compounds wit
