1325731-29-0Relevant articles and documents
Multicomponent macrocyclization reactions (MCMRs) employing highly reactive acyl ketene and nitrile oxide intermediates
Knapp, John M.,Fettinger, James C.,Kurth, Mark J.
supporting information; experimental part, p. 4732 - 4735 (2011/10/18)
An efficient synthesis of spiro-fused macrolactams by a multicomponent macrocyclization reaction (MCMR) is reported. The use of highly reactive, transient intermediates in this MCMR permits short reaction times, even at high dilution. The methods employed