1325835-88-8

Basic information

• Product Name: methyl 4-(3-benzylureido)benzoate
• Synonyms: methyl 4-(3-benzylureido)benzoate
• CAS NO: 1325835-88-8
• Molecular Weight: 284.315
• Mol File: 1325835-88-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 4-(3-benzylureido)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(3-benzylureido)benzoate(1325835-88-8)
• EPA Substance Registry System: methyl 4-(3-benzylureido)benzoate(1325835-88-8)

Safety Data

• Hazardous Substances Data: 1325835-88-8(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 3173-56-6 benzyl isothiocyanate 
• 619-45-4 4-methoxycarbonyl aniline 
• 1126-46-1 Methyl 4-chlorobenzoate 
• 538-32-9 benzylurea 

Downstream Products

• 30932-68-4 methyl 4-ureidobenzoate 

Relevant articles and documents

Design, synthesis and biological evaluation of urea-based benzamides derivatives as HDAC inhibitors

A new class of urea-based benzamides derivatives were designed and synthesized as histone deacetylases inhibitors. Biological evaluations of these compounds included the inhibitory activity of histone deacetylases1 and cytotoxicity against different cancer cell lines in vitro. Most compounds exhibited potential histone deacetylases inhibitory activity and antitumor activities. Compound 5h behaved as potent histone deacetylases1 inhibitor (IC50 = 0.182 μM) and showed comparable cytotoxicity with MS-275, which could be considered as a potential candidate compound for further development.