132589-73-2

Upstream product

• 104-01-8 4-Methoxyphenylacetic acid 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 132589-95-8 1-{2-[4-(4-Phenyl-furan-3-yl)-phenoxy]-ethyl}-piperidine 
• 132589-94-7 1-{2-[4-(4-Phenyl-furan-3-yl)-phenoxy]-ethyl}-pyrrolidine 
• 117319-88-7 3-(4-Hydroxy-phenyl)-4-phenyl-5H-furan-2-one 
• 117319-93-4 4-(4-Phenyl-furan-3-yl)-phenol 
• 1044169-24-5 3-[4-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-yl]-benzenesulfonyl chloride 
• 856659-46-6 2-[2-(4-methoxybenzyl)-4-phenylimidazol-1-ylmethyl]phenylamine 
• 856659-43-3 2-(4-methoxybenzyl)-1-(2-nitrobenzyl)-4-phenyl-1H-imidazole 
• 901125-15-3 2-(4-methoxybenzyl)-4-phenyl-1H-imidazole 
• 104594-83-4 Phenyl-(p-methoxyphenyl)-maleinsaeureanhydrid 
• 110836-02-7 3-(4-methoxyphenyl)-4-phenylfuran-2(5H)-one 

Relevant academic research and scientific papers

New application of Pictet-Spengler reaction leading to the synthesis of an unusual seven-membered heterocyclic ring system

A novel strategy for the Pictet-Spengler reaction is reported. Our strategy involves reaction of arylamines, linked to the N-1 of disubstituted imidazoles, with aldehydes in the presence of p-TsOH. The iminium ion generated in situ undergoes C-C bond form

Design and Synthesis of Novel Rofecoxib Analogs as Potential Cyclooxygenase (COX-2) Inhibitors: Replacement of the Methylsulfonyl Pharmacophore by a Sulfonylazide Bioisostere

A group of rofecoxib analogs, having a sulfonylazide (SO2N 3) substituent in place of the methanesulfonyl (SO2CH 3) pharmacophore at the meta-position viz 3-(4-methyl, 4-methoxy, or 4-ethoxyphenyl)-4-(3-sulfonyl