132606-75-8Relevant academic research and scientific papers
A one-pot synthesis of alkynyl sulfides from terminal alkynes
Zheng, Weixin,Zheng, Fenfen,Hong, Ya,Hu, Linfeng
, p. 105 - 110 (2012)
A one-pot synthesis of alkynyl sulfide from terminal alkyne has been reported via lithiation of the alkyne, oxidative addition of sulfur, consecutively followed by the nucleophilic substitution of lithium alkynyl thiolate to various halides.
Preparation of β-Hydroxysulfides from 1,2,3-Thiadiazoles. Comparison of the Effect of Phenylmagnesium Bromide on α-Thio- and α-Selenoketones
Ganjian, Iraj
, p. 2037 - 2039 (2007/10/02)
Base decomposition of 4-substituted-phenyl-1,2,3-thiadiazoles at 78 deg C resulted in 2-(4-substituted-phenyl)-ethynylthiolate anions which were immediately reacted with α-bromoketones to give a series of α-(2-ethynyl) thioketones.Unlike the selenophilic reaction of the Grignard reagents with α-selenoketones, the carbonyl group was the site of nucleophilic attack and the reaction of the α-thioketones with phenylmagnesium bromide gave the corresponding β-hydroxysulfides.The difference in mode of action toward the Grignard reagents was attributed to the difference in the bond strengths between carbon and the hetero-atoms.
