1326247-86-2Relevant academic research and scientific papers
Chemistry of ecteinascidins. Part 3: Preparation of 2′-N-acyl derivatives of ecteinascidin 770 and evaluation of cytotoxicity
Saktrakulkla, Panithi,Toriumi, Satoru,Tsujimoto, Mitsuhiro,Patarapanich, Chamnan,Suwanborirux, Khanit,Saito, Naoki
, p. 4421 - 4436 (2011/09/19)
A three-step transformation of ecteinascidin 770 (1b) into 2′-N-indole-3-carbonyl derivative 3 via 18,6′-O-bisallyl-protected derivative 4a, which was shown to have higher cytotoxicity than 1b, is presented. In addition, a number of 2′-N amide derivatives
