1326315-89-2Relevant academic research and scientific papers
Benzylic ligand hydroxylation starting from a dicopper μ- I·2:I·2 peroxo intermediate: Dramatic acceleration of the reaction by hydrogen-atom donors
Rolff, Malte,Hamann, Jessica Nadine,Tuczek, Felix
, p. 6924 - 6927 (2011)
Radicals in directed pathways: The μ-I·2: I·2 peroxo CuII2 intermediate 1 shows a much faster benzylic ligand hydroxylation than systems without phenol. This novel reactivity can be further accelerated by addition of external H-atom donors such as TEMPO-H. The results imply initial H-atom transfer leading to the formation of phenoxyl radicals. A highly reactive copper oxyl intermediate is then formed, which inserts oxygen into the benzylic C-H bond. Copyright
