13264-28-3Relevant academic research and scientific papers
Fluorine-substituted 1,2-Thiazetan-3-one 1-Oxides by Reaction of Bis(trifluoromethyl)ketene and N-Sulfinylamines
Jaeger, Ulrich,Schwab, Michael,Sundermeyer, Wolfgang
, p. 1127 - 1132 (2007/10/02)
4,4-Bis(trifluoromethyl)-1,2-thiazetan-3-one 1-oxides 3a-e are prepared by the reaction of bis(trifluoromethyl)ketene (1) with some N-sulfinylamines 2a-e.Under hydrolytic conditions the amides of 3,3,3-trifluoro-2-(trifluoromethyl)propionic acid 4a-e are formed, which are also obtained from 1 and the corresponding amines, especially C6F5NH2 and CF3NH2. 3e undergoes an unexpected thermolysis at room temperature with partial formation of trifluoromethyl isocyanate (5) and bis(trifluoromethyl)methylene sulfoxide (6).
