132644-74-7

Upstream product

• 100-64-1 cyclohexanone-oxime 
• 85540-20-1 2,3-bis(phenylsulfonyl)-1,3-butadiene 
• 132644-69-0 4,5-endo-bis(phenylsulfonyl)-7-oxa-1-azabicyclo<2.2.1>heptane-2-spiro-1'-cyclohexane 

Relevant academic research and scientific papers

Tandem Addition-Cycloaddition Reaction of Oximes with 2,3-Bis(phenylsulfonyl)-1,3-butadiene as a Method for 4-Piperidone Synthesis

The reaction of oximes with 2,3-bis(phenylsulfonyl)-1,3-butadiene affords 7-oxa-1-azanorbornanes in high yield.The formation of the bicyclic isoxazolidine involves conjugate addition of the oxime onto the diene to give a transient nitrone that ten undergo