132646-38-9

Upstream product

• 136058-82-7 4-(5-Bromo-benzofuran-2-ylmethyl)-2-cyclohexyl-5-methyl-oxazole 
• 1761-61-1 5-bromosalicyclaldehyde 
• 136058-86-1 2-(2-Cyclohexyl-5-methyl-oxazol-4-ylmethyl)-benzofuran-5-carbonitrile 

Downstream Products

• 136058-62-3 5-[1-[2-(2-Cyclohexyl-5-methyl-oxazol-4-ylmethyl)-benzofuran-5-yl]-meth-(Z)-ylidene]-2-thioxo-oxazolidin-4-one 
• 136058-63-4 5-[2-(2-Cyclohexyl-5-methyl-oxazol-4-ylmethyl)-benzofuran-5-ylmethyl]-oxazolidine-2,4-dione 

Relevant academic research and scientific papers

Benzyloxazolidine-2,4-diones as potent hypoglycemic agents

A series of benzyloxazolidine-2,4-diones, containing oxazole-based side chains, were found to lower blood glucose levels in the genetically obese ob/ob mouse. Incorporation of a benzofuran structural element in these compounds provides greatly enhanced in vivo potency. The syntheses and structure-activity relationships for this series are detailed.