132646-58-3

Upstream product

• 141820-37-3 2-(5-Methyl-2-p-tolyl-oxazol-4-ylmethyl)-benzofuran-5-carbonitrile 
• 141820-33-9 (5-Bromo-benzofuran-2-yl)-(5-methyl-2-p-tolyl-oxazol-4-yl)-methanol 
• 141820-35-1 4-[(5-bromo-1-benzofuran-2-yl)methyl]-5-methyl-2-(4-methylphenyl)-1,3-oxazole 
• 132646-36-7 2-<<5-methyl-2-(4-methylphenyl)-4-oxazolyl>methyl>benzofuran-5-carboxaldehyde 
• 344900-02-3 (5-bromo-1-benzofuran-2-yl)[5-methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]methanone 
• 1761-61-1 5-bromosalicyclaldehyde 

Relevant academic research and scientific papers

Benzyloxazolidine-2,4-diones as potent hypoglycemic agents

A series of benzyloxazolidine-2,4-diones, containing oxazole-based side chains, were found to lower blood glucose levels in the genetically obese ob/ob mouse. Incorporation of a benzofuran structural element in these compounds provides greatly enhanced in vivo potency. The syntheses and structure-activity relationships for this series are detailed.