132664-65-4Relevant academic research and scientific papers
STEREOSELECTIVE 1,3-DIPOLAR CYCLOADDITION OF UNSATURATED NITRILES TO ISOQUINOLINIUM YLIDS. MOLECULAR AND CRYSTAL STRUCTURE OF 1,2-trans-3,3-DICYANO-1-CARBAMOYL-2-(3-PYRIDYL)-1,2,3,4-TETRAHYDROBENZOINDOLIZINE
Shestopalov, A. M.,Sharanin, Yu. A.,Nesterov, V. N.,Rodinovskaya, L. A.,Shklover, V. E.,et al.
, p. 1006 - 1011 (2007/10/02)
The reactions of isoquinolinium ylids with arylmethylenemalononitriles proceed highly stereoselectively via a pathway involving synchronous 1,3-dipolar cycloaddition to give 1,2-trans-2-aryl-3,3-dicyano-1-carbamoyl(benzoyl)-1,2,3,4-tetrahydrobenzoindol
REGIO- AND STEREODIRECTIVITY IN THE REACTIONS OF ISOQUINOLINIUM YLIDES WITH UNSATURATED NITRILES
Shestopalov, A. M.,Rodinovskaya, L. A.,Sharanin, Yu. A.,Litvinov, V. P.
, p. 2348 - 2353 (2007/10/02)
Reactions of isoquinolinium ylides with arylmethylenemalonitriles involve 1,3-dipolar cycloaddition, with the highly regio- and stereoselective formation of 2-aryl-3-benzoyl(or carbamoyl)-1,1-dicyano-2,3-trans-1,2,3,10b-tetrahydropyrroloisoquinolines.In contrast, N-phenacylisoquinolinium ylide reacts with arylmethylenecyanothioacetamides differently, proceeding regio- and stereoselectively to give 4-aryl-2-hydroxy-3-(1-isoquinolinio)-2-phenyl-3-cyano-3,4-trans-1,2,3,4-tetrahydropyridine-6-thiolates.
