BIG ENDOTHELIN-2 (1-37) (HUMAN) is a naturally occurring peptide in the human body that plays a crucial role in regulating blood vessel constriction and dilation. It is a shortened form of the full-length protein, Big Endothelin-2, and contains the first 37 amino acids of the larger molecule. This peptide is a potent vasoconstrictor, meaning it causes blood vessels to narrow, leading to an increase in blood pressure. It also has the ability to stimulate the release of other hormones and proteins that further contribute to vasoconstriction. Due to its important role in regulating vascular function, BIG ENDOTHELIN-2 (1-37) (HUMAN) is the subject of research and potential therapeutic applications for various cardiovascular and circulatory disorders.
132699-72-0
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Basic information
- Product Name: BIG ENDOTHELIN-2 (1-37) (HUMAN)
- Synonyms: BIG ENDOTHELIN-2 (1-37) (HUMAN);BIG ET-2 (1-37) (HUMAN);BIG ENDOTHELIN 2 HUMAN;BIG ENDOTHELIN-2 (HUMAN, 1-37);CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-GLN-THR-ALA-PRO-TYR-GLY-LEU-GLY-ASN-PRO-PRO;H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-GLN-THR-ALA-PRO-TYR-GLY-LEU-GLY-ASN-PRO-PRO-OH;big endothelin 2
- CAS NO:132699-72-0
- Molecular Formula: C188H269N45O56S4
- Molecular Weight: 4183.68
- EINECS: N/A
- Product Categories: Endothelins;Peptides for Cell Biology;Precursors
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: BIG ENDOTHELIN-2 (1-37) (HUMAN)(CAS DataBase Reference)
- NIST Chemistry Reference: BIG ENDOTHELIN-2 (1-37) (HUMAN)(132699-72-0)
- EPA Substance Registry System: BIG ENDOTHELIN-2 (1-37) (HUMAN)(132699-72-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 132699-72-0(Hazardous Substances Data)
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132699-72-0 Usage
Uses
Used in Pharmaceutical Industry:BIG ENDOTHELIN-2 (1-37) (HUMAN) is used as a research tool for understanding the mechanisms of blood vessel constriction and dilation, which can help in the development of new drugs and therapies for cardiovascular and circulatory disorders.
Used in Biomedical Research:
BIG ENDOTHELIN-2 (1-37) (HUMAN) is used as a bioactive molecule to study the effects of vasoconstriction on blood pressure regulation and the release of other hormones and proteins involved in this process. This research can contribute to a better understanding of the underlying causes of various cardiovascular and circulatory disorders and the development of targeted treatments.
Used in Drug Development:
BIG ENDOTHELIN-2 (1-37) (HUMAN) is used as a potential therapeutic agent for the treatment of cardiovascular and circulatory disorders. Its vasoconstrictive properties can be harnessed to develop drugs that help regulate blood pressure and improve vascular function in patients with these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 132699-72-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,6,9 and 9 respectively; the second part has 2 digits, 7 and 2 respectively.Calculate Digit Verification of CAS Registry Number 132699-72:
(8*1)+(7*3)+(6*2)+(5*6)+(4*9)+(3*9)+(2*7)+(1*2)=150
150 % 10 = 0
So 132699-72-0 is a valid CAS Registry Number.
132699-72-0Upstream product
132699-72-0Downstream Products
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BIG ENDOTHELIN-2 (1-37) (HUMAN)
