1327160-69-9

Basic information

• Product Name: C₁₄H₁₁ClN₂O₄S
• Synonyms: C₁₄H₁₁ClN₂O₄S
• CAS NO: 1327160-69-9
• Molecular Weight: 338.771
• Mol File: 1327160-69-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₁ClN₂O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₁ClN₂O₄S(1327160-69-9)
• EPA Substance Registry System: C₁₄H₁₁ClN₂O₄S(1327160-69-9)

Safety Data

• Hazardous Substances Data: 1327160-69-9(Hazardous Substances Data)

Upstream product

• 1000933-19-6 methyl 4-chloro-3-(chlorosulfonyl)benzoate 
• 1670-14-0 benzamidine monohydrochloride 

Relevant articles and documents

A one-pot, non-catalytic approach to 1,2,4-benzothiadiazine-1,1-dioxides

Condensations of o-halo-substituted benzenesulfonyl chlorides with 2-aminopyridines and amidines may give the corresponding 1,2,4-benzothiadiazine- 1,1-dioxides under mild, non-catalytic conditions in nearly quantitative yields. The successful one-pot cyclization depends on three factors: (i) the nature of the o-halogen, (ii) the electronic character of the benzene ring substituent, and (iii) the steric load around the amidine unit. O-Fluorobenzenesulfonyl chlorides bearing methylcarboxyl- or nitro-group and o-chloro- and o-bromobenzenesulfonyl chlorides bearing nitro-group are reactive enough to give the desired 1,2,4-benzothiadiazine-1,1-dioxides in a one-pot base-promoted reaction. In all other cases, open-chain sulfonylated amidine intermediates are isolated. The latter are converted to the title compounds either in the presence of potassium carbonate or upon the addition of a copper(I) catalyst.