1327166-04-0Relevant academic research and scientific papers
Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk)
Rosenthal, Andrew S.,Tanega, Cordelle,Shen, Min,Mott, Bryan T.,Bougie, James M.,Nguyen, Dac-Trung,Misteli, Tom,Auld, Douglas S.,Maloney, David J.,Thomas, Craig J.
scheme or table, p. 3152 - 3158 (2011/06/24)
Continued examination of substituted 6-arylquinazolin-4-amines as Clk4 inhibitors resulted in selective inhibitors of Clk1, Clk4, Dyrk1A and Dyrk1B. Several of the most potent inhibitors were validated as being highly selective within a comprehensive kino
