132741-54-9

Basic information

• Product Name: D-digitoxonic acid lactone
• CAS NO: 132741-54-9
• Molecular Weight: 146.143
• Mol File: 132741-54-9.mol

Chemical Properties

• CAS DataBase Reference: D-digitoxonic acid lactone(CAS DataBase Reference)
• NIST Chemistry Reference: D-digitoxonic acid lactone(132741-54-9)
• EPA Substance Registry System: D-digitoxonic acid lactone(132741-54-9)

Safety Data

• Hazardous Substances Data: 132741-54-9(Hazardous Substances Data)

Upstream product

• 2053-00-1 D-digitoxose 
• 862900-35-4 (1R,4R,5R,6R)-5-Hydroxy-4-methyl-3,7-dioxa-bicyclo[4.1.0]heptan-2-one 
• 476468-23-2 (R)-but-3-enoic acid 1-methyl-allyl ester 
• 121313-24-4 (4S,5R)-4-hydroxy-2-hexen-5-olide 
• 118992-11-3 (-)-6-(6R)-methyldihydropyr-4-en-2-one 

Relevant articles and documents

A divergent synthesis of uncommon sugars from furanaldehyde

A practical synthetic strategy has been developed for producing uncommon sugars. This method employed kinetic enzymatic resolution of 1-(2-furyl)ethanol, and followed by NBS-mediated Achmatowicz rearrangement to construct α,β-unsaturated lactones. After further derivatization, five representative uncommon sugar units were successfully synthesized. Georg Thieme Verlag Stuttgart.

Synthesis of 2,6-dideoxysugars via ring-closing olefinic metathesis.

[formula: see text] Grubbs' RuCl2 (=CHPh)(PCy3)2 (catalyst 1) and RuCl2(=CHPh)(PCy3)(IMess) (catalyst 2) complexes have been successfully utilized in the construction of beta,gamma-unsaturated delta-lactones containing various substitution patterns of methyl groups. Asymmetric dihydroxylation followed by reduction leads to 3,4-cis-dihydroxy-2,6-dideoxypyranoses, which have proven to play very important biological roles as key components of natural products.