132766-78-0

Basic information

• Product Name: (5-PYRIDIN-4-YL-TETRAZOL-2-YL)-ACETIC ACID
• Synonyms: (5-PYRIDIN-4-YL-TETRAZOL-2-YL)-ACETIC ACID;CBI-BB ZERO/005849;ASINEX-REAG BAS 12777159;2-(5-(pyridin-4-yl)-2H-tetrazol-2-yl)acetic acid
• CAS NO: 132766-78-0
• Molecular Formula: C8H7N5O2
• Molecular Weight: 205.17
• Mol File: 132766-78-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (5-PYRIDIN-4-YL-TETRAZOL-2-YL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (5-PYRIDIN-4-YL-TETRAZOL-2-YL)-ACETIC ACID(132766-78-0)
• EPA Substance Registry System: (5-PYRIDIN-4-YL-TETRAZOL-2-YL)-ACETIC ACID(132766-78-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• HazardClass: IRRITANT
• Hazardous Substances Data: 132766-78-0(Hazardous Substances Data)

Usage

General Description

(5-Pyridin-4-yl-tetrazol-2-yl)-acetic acid is a chemical compound with the molecular formula C9H8N4O2. It consists of a pyridine ring attached to a tetrazole ring, which in turn is linked to an acetic acid group. (5-PYRIDIN-4-YL-TETRAZOL-2-YL)-ACETIC ACID is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs. It has potential applications in the development of antihypertensive, antithrombotic, and anti-inflammatory medications. Additionally, it has also demonstrated antimicrobial and antifungal properties, making it a versatile and valuable chemical in the field of medicinal chemistry.

Upstream product

• 105-36-2 ethyl bromoacetate 
• 14389-12-9 4-(1H-tetrazol-5-yl)-pyridine 

Relevant articles and documents

Nitrogen-rich 5-(4-pyridyl)tetrazole-2-acetic acid and its alkaline earth metal coordination polymers for potential energetic materials

Tetrazole and its derivatives with rich nitrogen atoms may be potential candidates for energetic materials. Alkaline earth metal coordination compounds based on such ligands are relatively less investigated. Hpytza was prepared from 4-cyanopyridine and sodium azide, ethyl bromoacetate, where Hpytza = 5-(4-pyridyl)tetrazole-2-acetic acid. Hpytza and four alkaline earth metal coordination polymers [Mg(pytza)2]n (1), [Ca(pytza)2(H2O)2]n·3nH2O (2), [Sr(pytza)2(H2O)2]n (3) and [Ba(pytza)2(H2O)2]n·nH2O (4) were prepared under solvothermal conditions. The thermal behavior of these compounds were characterized by the differential scanning calorimetry (DSC) and thermogravimetric-differential thermogravimetric (TG-DTG) analyses. Furthermore, the critical temperature of thermal explosion and relevant thermal parameters ΔS, ΔH, ΔG of Hpytza and polymers 1-4 were calculated, as well, indicating that these compounds are potential energetic materials.