132774-40-4

Basic information

• Product Name: 1-[(2-Fluoroethoxy)methyl]-6-(phenylthio)thymine
• Synonyms: 1-((2-Fluoroethoxy)methyl)-6-(phenylthio)thymine; 1-[(2-Fluoroethoxy)methyl]-6-(phenylthio)thymine; 2,4(1H,3H)-Pyrimidinedione, 1-((2-fluoroethoxy)methyl)-5-methyl-6-(phenylthio)-; 2,4(1H,3H)-pyrimidinedione, 1-[(2-fluoroethoxy)methyl]-5-methyl-6-(phenylthio)-
• CAS NO: 132774-40-4
• Molecular Formula: C₁₄H₁₅FN₂O₃S
• Molecular Weight: 310.3439
• Mol File: 132774-40-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.35g/cm³
• Refractive Index: 1.604
• CAS DataBase Reference: 1-[(2-Fluoroethoxy)methyl]-6-(phenylthio)thymine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(2-Fluoroethoxy)methyl]-6-(phenylthio)thymine(132774-40-4)
• EPA Substance Registry System: 1-[(2-Fluoroethoxy)methyl]-6-(phenylthio)thymine(132774-40-4)

Safety Data

• Hazardous Substances Data: 132774-40-4(Hazardous Substances Data)

Usage

Chemical class

Thymidine analog

Target

Human immunodeficiency virus (HIV) and other retroviruses

Mechanism of action

Nucleoside reverse transcriptase inhibitor (NRTI)

Function

Blocks the enzyme required for viral replication

Purpose

Inhibits the spread and multiplication of the virus in the body

Potential use

Development of new antiretroviral drugs

Structure

Promising for further research and development in antiviral medications

InChI:InChI=1/C14H15FN2O3S/c1-10-12(18)16-14(19)17(9-20-8-7-15)13(10)21-11-5-3-2-4-6-11/h2-6H,7-9H2,1H3,(H,16,18,19)

Upstream product

• 132774-38-0 1-(2-Fluoro-ethoxymethyl)-5-methyl-1H-pyrimidine-2,4-dione 
• 882-33-7 diphenyldisulfane 

Relevant articles and documents

Specific anti-HIV-1 ''acyclonucleosides'' which cannot be phosphorylated: Synthesis of some deoxy analogues of 1-](2-hydroxyethoxy)methyl]-6-(phenylthio)thymine [3]

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