132776-20-6

Basic information

• Product Name: 1-(5-O-benzoyl-2,3-dideoxy-2,3-difluoro-beta-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
• Synonyms: 1-(5-O-Benzoyl-2,3-dideoxy-2,3-difluoro-.beta.-D-arabinofuranosyl)thymine; 1-(5-O-Benzoyl-2,3-dideoxy-2,3-difluoro-beta-D-arabinofuranosyl)thymine
• CAS NO: 132776-20-6
• Molecular Formula: C₁₇H₁₆F₂N₂O₅
• Molecular Weight: 366.3161
• Mol File: 132776-20-6.mol
• Article Data: 1

Chemical Properties

• Density: 1.43g/cm³
• Refractive Index: 1.577
• CAS DataBase Reference: 1-(5-O-benzoyl-2,3-dideoxy-2,3-difluoro-beta-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-O-benzoyl-2,3-dideoxy-2,3-difluoro-beta-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione(132776-20-6)
• EPA Substance Registry System: 1-(5-O-benzoyl-2,3-dideoxy-2,3-difluoro-beta-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione(132776-20-6)

Safety Data

• Hazardous Substances Data: 132776-20-6(Hazardous Substances Data)

Upstream product

• 69256-17-3 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)thymine 
• 98-88-4 benzoyl chloride 
• 132776-19-3 2,3'-anhydro-1-(5-O-benzoyl-2-deoxy-2-fluoro-D-lyxofuranosyl)thymine 

Downstream Products

• 132776-22-8 1-(5-O-benzoyl-2,3-dideoxy-2,3-difluoro-β-D-arabinofuranosyl)-4-thiothymidine 
• 132776-21-7 1-(2,3-dideoxy-2,3-difluoro-β-D-arabinofuranosyl)thymine 
• 132776-23-9 1-(2,3-dideoxy-2,3-difluoro-β-D-arabinofuranosyl)-5-methylcytosine 

Relevant articles and documents

Fluorinated sugar analogues of potential anti-HIV-1 nucleosides

In order to obtain agents with therapeutic indices superior to those of AZT, FLT, or D4T, several analogues of anti-HIV-1 nucleosides were synthesized. These include 2',3'-dideoxy-2',3'-difluoro-5-methyluridine (13), its arabino analogue 19, arabino-5-met