132776-30-8 Usage
General Description
1-(2,3-Dideoxy-2-fluoro-5-O-trityl-.beta.-D-erythro-pentofuranosyl)thymine is a chemical compound with the molecular formula C31H29FNO5. It is a derivative of thymine, a nucleoside found in DNA. 1-(2,3-Dideoxy-2-fluoro-5-O-trityl-.beta.-D-erythro-pentofuranosyl)thymine consists of a thymine base bound to a sugar molecule with a trityl group protecting the hydroxyl group at the 5' carbon. The 2' and 3' hydroxyl groups of the sugar molecule are absent, making it a dideoxy compound. The presence of a fluoro group at the 2' carbon of the sugar molecule and a trityl group on the 5' carbon make this compound useful in the synthesis and study of nucleic acids and nucleoside analogs. Its properties make it potentially valuable in pharmaceutical research for the development of antiviral drugs and treatments for genetic disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 132776-30-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,7,7 and 6 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 132776-30:
(8*1)+(7*3)+(6*2)+(5*7)+(4*7)+(3*6)+(2*3)+(1*0)=128
128 % 10 = 8
So 132776-30-8 is a valid CAS Registry Number.
132776-30-8Relevant articles and documents
Fluorinated sugar analogues of potential anti-HIV-1 nucleosides
Huang,Chen,Wang,Kim,Warshaw,Armstrong,Zhu,Chou,Watanabe,Matulic-Adamic,Su,Fox,Polsky,Baron,Gold,Hardy,Zuckerman
, p. 1640 - 1646 (2007/10/02)
In order to obtain agents with therapeutic indices superior to those of AZT, FLT, or D4T, several analogues of anti-HIV-1 nucleosides were synthesized. These include 2',3'-dideoxy-2',3'-difluoro-5-methyluridine (13), its arabino analogue 19, arabino-5-met