132802-63-2

Upstream product

• 132802-62-1 1-(tert-Butyldimethylsiloxy)-3-(allyloxy)benzene 

Downstream Products

• 132802-72-3 (+/-)-trans-2-(3,4-dimethoxyphenyl)-2,3-dihydro-5-allyl-6-(allyloxy)-3-methylbenzofuran 
• 104265-73-8 rac-(2S,3S)-5-allyl-6-hydroxy-2-(3,4-dimethoxyphenyl)-3-methyl-2,3-dihydrobenzofuran 
• 132802-71-2 4-allyl-3-(allyloxy)phenol 

Relevant academic research and scientific papers

Boron trichloride mediated regioselective Claisen rearrangement of resorcinol derivatives: Application to resorcinol carvonyl ethers

Claisen rearrangement (CR) of resorcinol allyl ethers was examined. Although thermal CR gave low regioselectivity, the selectivity was much improved in the presence of a Lewis acid such as boron trichloride. This rearrangement was successfully applied to resorcinol carvonyl ethers for the regioselective introduction of a carvone unit into the resorcinol skeleton for the synthesis of phytoestrogenic miroestrols. Georg Thieme Verlag Stuttgart.

A Convergent Route to Dihydrobenzofuran Neolignans via a Formal 1,3-Cycloaddition to Oxidized Phenols

Oxidation of p-methoxy-substituted phenols with iodobenzene bis-trifluoroacetate in the presence of electron-rich styrene derivatives affords trans-dihydrobenzofurans stereoselectively.