132819-80-8Relevant academic research and scientific papers
Palladium-catalyzed oxidative heck-type allylation of β,β- disubstituted enones with allyl carbonates
Jin, Weiwei,Yang, Qin,Wu, Ping,Chen, Jiping,Yu, Zhengkun
supporting information, p. 2097 - 2102 (2014/07/07)
The palladium-catalyzed oxidative Heck-type allylation of β,β-disubstituted enones, i.e., α-oxoketene dithioacetals, was efficiently realized with allyl carbonates, providing a concise route to highly functionalized dienes. The present synthetic methodology utilizes the substrate activation strategy to activate the C-H bond of β,β-disubstituted enones by introduction of a 1,2-dithiolane functionality to make the enone substrate highly polarized and thus increase its reactivity, demonstrating rare examples for transition metal-catalyzed allylic substitution of ss,ss-disubstituted enones through a Heck-type allylation process.
PALLADIUM-CATALYZED REACTION OF 3-BROMOINDOLE DERIVATIVE WITH ALLYL ESTERS IN THE PRESENCE OF HEXA-n-BUTYLDISTANNANE
Yokoyama, Yuusaku,Ikeda, Masato,Saito, Masaaki,Yoda, Tomoko,Suzuki, Hideharu,Murakami, Yasuoki
, p. 1505 - 1511 (2007/10/02)
The palladium-catalyzed cross-coupling reaction of ethyl 3-bromo-1-tosylindole-2-carboxylate (9) with a variety of substituted allylic acetates or carbonates (10) in the presence of hexa-n-butyldistannane (6) gave 3-allylated indoles (11) in high yields.
