132832-30-5Relevant academic research and scientific papers
Substituted azetidinylpyridone naphthyridine carboxylic acid derivatives and their application as medical products
-
, (2008/06/13)
The present invention relates to new azetidine derivatives of substituted azetidinylpyridonecarboxylic acids, of 1,4-dihydro-4-oxo-3-quinolinecarboxylic, 4-oxo-1,8-naphthyridine-3-carboxylic and 2,3-dihydro-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acids, represented by the general formula I: STR1 The present invention also relates to therapeutically acceptable salts of these compounds, a process for preparing them and their application as medicinal products.
7-Azetidinylquinolones as Antibacterial Agents. 3. Synthesis, Properties and Structure-Activity Relationships of the Stereoisomers Containing a 7-(3-Amino-2-methyl-1-azetidinyl) Moiety
Frigola, Jordi,Vano, David,Torrens, Antoni,Gomez-Gomar, Angels,Ortega, Edmundo,Garcia-Granda, Santiago
, p. 1203 - 1215 (2007/10/02)
A series of stereochemically pure 7-(3-amino-2-methyl-1-azetidinyl)-1,4-dihydro-6-fluoro-4-oxoquinoline- and -1,8-naphthyridine-3-carboxylic acids, with varied substituents at the 1-, 5-, and 8-positions, was prepared to determine the effects of chirality
