132834-59-4

Usage

Uses

Used in Pharmaceutical Industry:
1-[3-Chloro-5-(trifluoromethyl)pyrid-2-yl]piperazine is used as a key intermediate in the synthesis of various pharmaceutical compounds for its potential applications in the treatment of neurological disorders and psychiatric illnesses. Its unique structure allows for the development of new drugs that can target specific receptors or pathways involved in these conditions, offering novel therapeutic options.
Used in Research Chemicals:
In the field of research, 1-[3-Chloro-5-(trifluoromethyl)pyrid-2-yl]piperazine serves as a valuable chemical entity for the exploration of new drug candidates and the study of biological mechanisms. Its synthesis and modification can provide insights into the structure-activity relationships of potential drugs, aiding in the optimization of their pharmacological properties.
Used in Agrochemical Industry:
1-[3-Chloro-5-(trifluoromethyl)pyrid-2-yl]piperazine has also been investigated for its possible use as an insecticide and acaricide. Its chemical properties and potential biological activity make it a candidate for the development of new agrochemicals to control pests and parasites in agriculture, thereby contributing to increased crop yields and reduced damage to plants.

InChI:InChI=1/C10H11ClF3N3/c11-8-5-7(10(12,13)14)6-16-9(8)17-3-1-15-2-4-17/h5-6,15H,1-4H2

Upstream product

• 110-85-0 piperazine 
• 69045-84-7 2,3-dichloro-5-trifluoromethylpyridine 

Downstream Products

• 260553-15-9 PCM-0102378 
• 1055353-49-5 C₂₁H₂₀ClF₆N₃O₄S 

Relevant academic research and scientific papers

Fluorine-containing pyridine acyl piperazine compound and application thereof

The invention provides a fluorine-containing pyridine acyl piperazine compound. The structure is shown in the general formula I shown in the description, and R in the formula is shown in the description. The compound in the general formula I has the excellent insecticidal activity and can be used as an insecticide to be used for pest control for agriculture and forestry.

Fluorine-containing pyridine piperazine imidazole carbamide, and applications thereof

The invention discloses a fluorine-containing pyridine piperazine imidazole carbamide compound. The structure of the fluorine-containing pyridine piperazine imidazole carbamide compound is representedby formula I. The fluorine-containing pyridine piperazine imidazole carbamide compound possesses excellent bactericidal activity on A. solani, C. cucumerinum, C, rachidicola, Botryosphaeria dothidea,and Phytophthora capsici Leonian, and can be used for agriculture or forestry bacterial disease control.

Fluorine-containing pyridine piperazine urea compound and application thereof

The invention discloses a fluorine-containing pyridine piperazine urea compound. The structure is as shown in the formula I which is as shown in the description. The compound as shown in the formula Ihas effects of restraining and killing pest mites and mite eggs and can be used as an acaricide for controlling agricultural pest mites.

Fluoropyridine-containing piperazine amide compounds and application thereof

The invention provides fluoropyridine-containing piperazine amide compounds. The structure of the compounds is represented as the general formula I shown in the description, wherein R in the formula is as follows: C1-C5 alkyl, C1-C4 alkoxy, substituted phenyl and heterocyclic aryl. The compounds shown as the formula I have inhibiting and killing effects on harmful mites and mite eggs, and can be taken as miticides to be applied to control of agricultural and forestry mite damage.

AMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF

Amide compounds, preparation methods and uses thereof. The structure of the compounds is represented as the general formula (I), in which the definitions of substituents are illuminated as description. The present amide compounds have broad spectrum activ

PROLINE DERIVATIVES AND USE THEREOF AS DRUGS

The present invention aims at providing compounds having therapeutic effects due to a DPP-IV inhibitory action, and satisfactory as pharmaceutical products. The present inventors have found that derivatives having a substituent introduced into the γ-position of proline represented by the formula (I) wherein each symbol is as defined in the specification, have a potent DPP-IV inhibitory activity, and completed the present invention by increasing the stability.

PHARMACEUTICAL COMPOSITION CONTAINING 1-(MONO- OR BIS(TRIFLUOROMETHYL)-2-PYRIDINYL)-PIPERAZINES

Pharmaceutical composition which is useful as a medicinal product, in particular for the treatment of disorders of the central nervous system, characterized in that it contains customary pharmaceutical excipients, and at least one of the compounds of formula STR1 in which the trifluoromethyl substituent is at the 4-position, at the 5-position, or at 4-and 5-positions of the pyridinyl ring, and the substituent R denotes either hydrogen or a halogen, such as chlorine, at position(s) of the pyridinyl ring not occupied by CF 3, and its pharmaceutically acceptable salts.