132835-08-6 Usage
Structure
Contains an aziridine ring and a sulfonamide group The aziridine ring is a three-membered ring with two carbon atoms and one nitrogen atom, while the sulfonamide group is a sulfur atom double-bonded to oxygen and single-bonded to nitrogen and carbon atoms.
Stereocenter
Two possible enantiomers The presence of a stereocenter (a carbon atom bonded to four different groups) gives the compound two possible mirror-image forms, known as enantiomers.
Uses
Commonly used in the synthesis of pharmaceuticals, agrochemicals, and industrial chemicals 2,3-Aziridinedimethanol, 1-[(4-methylphenyl)sulfonyl]-, (2R,3S)-rel- is used as a building block or intermediate in the production of a variety of chemicals, including drugs and pesticides.
Hazards
Can pose potential hazards to human health and the environment if not handled properly As with any chemical, it is important to handle 2,3-Aziridinedimethanol, 1-[(4-methylphenyl)sulfonyl]-, (2R,3S)-rel- with care and follow proper safety procedures to minimize the risk of exposure and harm.
Check Digit Verification of cas no
The CAS Registry Mumber 132835-08-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,8,3 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 132835-08:
(8*1)+(7*3)+(6*2)+(5*8)+(4*3)+(3*5)+(2*0)+(1*8)=116
116 % 10 = 6
So 132835-08-6 is a valid CAS Registry Number.
132835-08-6Relevant academic research and scientific papers
Palladium(II) mediated aziridination of olefins with bromamine-T as the nitrogen source: scope and mechanism
Antunes, Alexandra M.M.,Bonifácio, Vasco D.B.,Nascimento, Susana C.C.,Lobo, Ana M.,Branco, Paula S.,Prabhakar, Sundaresan
, p. 7009 - 7017 (2008/02/05)
The palladium(II)-promoted reaction of a variety of olefins and bromamine-T provided N-tosyl-2-substituted aziridines under mild conditions. Olefins bearing chiral appendages gave only a poor to modest diastereoselectivity. Appropriate deuterated olefins
Base promoted isomerization of aziridinyl ethers: a new access to alpha- and beta-amino acids.
Mordini, Alessandro,Sbaragli, Laura,Valacchi, Michela,Russo, Francesco,Reginato, Gianna
, p. 778 - 779 (2007/10/03)
Aziridinyl ethers are selectively and easily converted to either amino vinyl ethers or alkoxy allylamines by treatment with mixed metal bases (superbases).
A new access to chiral aziridines by enzymatic transesterification of meso-bis(acetoxymethyl)aziridines
Fuji,Kawabata,Kiryu,Sugiura,Taga,Miwa
, p. 6663 - 6666 (2007/10/02)
(2R,3S)-2-acetoxymethyl-3-hydroxymethylazirizines of high enantiomeric purity were prepared through enzymatic transesterification of meso-bis(acetoxymethyl)aziridines.
