132858-47-0

Basic information

• Product Name: 1-(3,4-dimethoxyphenyl)-3-methylbutan-1-one
• Synonyms: 1-(3,4-dimethoxyphenyl)-3-methylbutan-1-one
• CAS NO: 132858-47-0
• Molecular Weight: 222.284
• Mol File: 132858-47-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(3,4-dimethoxyphenyl)-3-methylbutan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4-dimethoxyphenyl)-3-methylbutan-1-one(132858-47-0)
• EPA Substance Registry System: 1-(3,4-dimethoxyphenyl)-3-methylbutan-1-one(132858-47-0)

Safety Data

• Hazardous Substances Data: 132858-47-0(Hazardous Substances Data)

Usage

General Description

1-(3,4-dimethoxyphenyl)-3-methylbutan-1-one, also known as Paeonol, is a chemical compound that is derived from the natural product paeony root. It is a secondary metabolite found in various plants and possesses a wide range of biological activities, including anti-inflammatory, antioxidant, and anti-cancer properties. Paeonol has been extensively studied for its potential therapeutic effects, particularly in the treatment of inflammatory and immune-related conditions. It is also being investigated for its potential use in skincare products due to its antioxidant and anti-aging properties. Additionally, paeonol has shown promise as a potential treatment for neurodegenerative diseases, such as Alzheimer's and Parkinson's, due to its neuroprotective effects. Overall, paeonol has demonstrated diverse pharmacological activities and potential therapeutic applications in the fields of medicine and skincare.

Upstream product

• 91-16-7 1,2-dimethoxybenzene 
• 108-12-3 isopentanoyl chloride 
• 503-74-2 3-methylbutyric acid 

Downstream Products

• 1381862-17-4 C₁₆H₂₂O₃ 
• 1381862-25-4 C₁₇H₂₂O₅ 
• 100523-44-2 2-isopentyl-4,5-dimethoxy-benzenesulfonic acid amide 
• 362467-67-2 7-(3'-methylbutyl)benzo[b][1,4]dioxepin-3-one 
• 2525-09-9 4-isopentyl-pyrocatechol 
• 108996-61-8 1,2-dimethoxy-4-(3-methylbutyl)benzene 

Relevant articles and documents

DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS

Disclosed are compounds of Formula (I) or a salt thereof, wherein R1, R3, R4, R5, m, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.

SUBSTITUTED 6,7-DIALKOXY-3-ISOQUINOLINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASE 10 (PDE10A)

The invention relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein R', R1 through R7 and Ar are as defined herein. These compounds are useful as inhibitors of phosphodiesterase 10 (PDE10A) which are useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type II diabetes, metabolic syndrome, glucose intolerance, pain and ophthalmic diseases.

Conception, characterization and correlation of new marine odorants

Via a synthetic sequence consisting of PPA-mediated Friedel-Crafts acylation of veratrol (8), Clemmensen reduction, demethylation with TMSI, Williamson ether synthesis employing 3-chloro-2-(chloromethyl)prop-1-ene and in-situ ruthenium tetroxide oxidation, numerous substituted benzo[b][1,4]dioxepinones 15-27 and 2,3-dihydro-1H-5,9-di-oxacyclohepta[f]indenones 7, 13 and 14 were prepared to study their odor-structure correlation. In the course of these studies, we discovered the extremely powerful new marine odorant 7-(3′ -methylbutyl)benzo[b][1,4]dioxepin-3-one (16). On the basis of the measured odor threshold data, an olfactophore model was constructed that rationalizes the observed odor intensities, and indicates an aliphatic hydrophobe at a distance of 6.3 A from the centre of the aromatic-ring binding site. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.