13286-35-6Relevant academic research and scientific papers
A facile and efficient microwave-mediated S-alkylation of thiophosphates
Pandey, Lokesh Kumar,Mazumder, Avik,Pathak, Uma
experimental part, p. 602 - 605 (2010/01/06)
A convenient, highly efficient, safe microwave-mediated S- alkylation of O,O'-dialkyl thiophosphate has been reported. Clean and rapid S-alkylation of thiophosphates can be achieved by irradiating a mixture of dialkylthiophosphate salt and alky! halide under microwave for a brief period. Alkylation occurs exclusively at sulfur to provide S-alkylated products. Through a simple workup, pure compounds have been obtained easily in good yields.
Process for the preparation of O,O-dialkyl-S-benzyl thiophosphates
-
, (2008/06/13)
O,O-Dialkyl-S-benzyl thiophosphates are obtained by reacting a diester of phosphorous acid such as dimethyl phosphite or diethyl phosphite, in an organic solvent such as toluene or xylene which is sparingly soluble or insoluble in water, with sulfur and an alkali or alkaline earth metal hydroxide or oxide such as NaOH or Ca(OH)2, extracting the reaction product with water and then reacting the extract with a benzyl halide. In this manner, O,O-dialkyl-S-benzyl thiophosphates useful as agricultural and horticultural bactericidal and insecticidal agents are industrially advantageously obtained in a high purity and in a high yield.
