132869-25-1Relevant articles and documents
Preparation of mono-labelled aliphatic polyacids via isoxazole derivatives
Adamo, Mauro F.A.,Sarti-Fantoni, Piero,Chimichi, Stefano,Sandrelli, Alessandro
scheme or table, p. 6310 - 6312 (2011/01/04)
A method allowing the selective oxygen labelling of aliphatic polyacids, for example, succinic and glutaric acids, is reported. This process is based on the hydrolysis of a 3-alkyl-4-nitroisoxazol-5-yl group by Na18OH and affords the products i
PREPARATION OF 5,6,7,8-TETRAHYDRO-7-ARYL-3-METHYLISOXAZOLOAZEPIN-5(4H)-ONES
Baracchi, Antonella,Chimichi, Stefano,Sio, Francesco De,Donati, Donato,Polo, Cecilia,Sarti-Fantoni, Piero
, p. 1823 - 1831 (2007/10/02)
3-Methyl-4-nitro-5-styrylisoxazoles (1a-e) reacted with diethyl malonate to give the corresponding Michael adducts (2a-e) which have been hydrolyzed to 4-(3-methyl-4-nitroisoxazol-5-yl)-3-phenyl(chlorophenyl)butanoic acids (3a-e).Subsequent reduction of t