132872-29-8Relevant academic research and scientific papers
Synthesis of (+/-)-Thienamycin based on a New Approach to β-Lactams via 4-Exo-trig Cyclisation of Carbamoylcobalt Salophens
Pattenden, Gerald,Reynolds, Stephen J.
, p. 379 - 386 (1994)
A series of N-propenyl substituted N-benzylcarbamoylcobalt(III) salophens, i.e., 11, 20 and 30, have been prepared, and have been shown to be useful precursors in a new approach to β-lactams (viz. 12 - 16, 21 and 31) via 4-exo-trig-modes of cyclisation of
A new synthetic route to (±)-thienamycin via 4-exo trigonal cyclisation of carbamoyl cobalt intermediates
Pattenden, Gerald,Reynolds, Stephen J.
, p. 259 - 262 (2007/10/02)
A new synthesis of (±)-thienamycin (1), based on elaboration of the key intermediate (12) in one step by heating a solution of the carbamoylcobalt salophen (11) in toluene, is described.
