132877-27-1

Basic information

• Product Name: 5-(trifluoromethoxy)-1H-benzimidazol-2-amine
• Synonyms: 1H-benzimidazol-2-amine, 6-(trifluoromethoxy)-; 6-(Trifluoromethoxy)-1H-benzimidazol-2-amine
• CAS NO: 132877-27-1
• Molecular Formula: C₈H₆F₃N₃O
• Molecular Weight: 217.1479
• Mol File: 132877-27-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 337.9°C at 760 mmHg
• Flash Point: 158.2°C
• Density: 1.576g/cm³
• Vapor Pressure: 0.000102mmHg at 25°C
• Refractive Index: 1.613
• CAS DataBase Reference: 5-(trifluoromethoxy)-1H-benzimidazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(trifluoromethoxy)-1H-benzimidazol-2-amine(132877-27-1)
• EPA Substance Registry System: 5-(trifluoromethoxy)-1H-benzimidazol-2-amine(132877-27-1)

Safety Data

• Hazardous Substances Data: 132877-27-1(Hazardous Substances Data)

Usage

Description

5-(trifluoromethoxy)-1H-benzimidazol-2-amine, also known as TFB, is a chemical compound with the molecular formula C8H5F3N4O. It is a white to off-white solid that is commonly used as a building block in organic synthesis and pharmaceutical research. TFB is known for its potent antimicrobial and antifungal properties, making it a valuable compound in the development of new medications. Additionally, it has been studied for its potential use in the treatment of cancer and other diseases. Due to its unique chemical structure and versatile properties, TFB is a valuable tool in the field of medicinal chemistry and drug discovery.

Uses

Used in Pharmaceutical Industry:
5-(trifluoromethoxy)-1H-benzimidazol-2-amine is used as a building block in organic synthesis for the development of new medications, particularly due to its potent antimicrobial and antifungal properties.
Used in Medicinal Chemistry:
5-(trifluoromethoxy)-1H-benzimidazol-2-amine is used as a valuable tool in medicinal chemistry for drug discovery, given its unique chemical structure and versatile properties.
Used in Antimicrobial Applications:
5-(trifluoromethoxy)-1H-benzimidazol-2-amine is used as an antimicrobial agent for the development of new medications to combat resistant bacteria and fungi.
Used in Antifungal Applications:
5-(trifluoromethoxy)-1H-benzimidazol-2-amine is used as an antifungal agent for the development of new medications to treat fungal infections.
Used in Cancer Treatment Research:
5-(trifluoromethoxy)-1H-benzimidazol-2-amine is used in research for its potential use in the treatment of cancer, as it has been studied for its possible therapeutic effects against various types of cancer.