13289-27-5

Basic information

• Product Name: Urea, N-(2-methylphenyl)-N'-4-pyridinyl-
• CAS NO: 13289-27-5
• Molecular Formula: C13H13N3O
• Molecular Weight: 227.266
• Mol File: 13289-27-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Urea, N-(2-methylphenyl)-N'-4-pyridinyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Urea, N-(2-methylphenyl)-N'-4-pyridinyl-(13289-27-5)
• EPA Substance Registry System: Urea, N-(2-methylphenyl)-N'-4-pyridinyl-(13289-27-5)

Safety Data

• Hazardous Substances Data: 13289-27-5(Hazardous Substances Data)

Upstream product

• 504-24-5 4-aminopyridine 
• 614-68-6 2-tolyl isocyanate 
• 4013-73-4 isonicotinoyl azide 
• 95-53-4 o-toluidine 
• 201230-82-2 carbon monoxide 

Relevant articles and documents

Phosgene-free synthesis of N-Aryl-N'-(4-pyridinyl)ureas via selenium-catalyzed oxidative carbonylation of 4-Aminopyridine with aromatic amines

A facile, phosgene-free approach with high atom economy has been developed for the synthesis of N-Aryl-N'-(4-pyridinyl)ureas. With cheap selenium as the catalyst, carbon monoxide (instead of phosgene) as the carbonyl reagent, N-Aryl-N'-(4-pyridinyl)ureas can be obtained in a one-pot manner mostly in moderate to good yields via oxidative cross-carbonylation of 4-Aminopyridine with a variety of aromatic amines in the presence of oxygen under atmospheric pressure. The mechanism for the synthesis of N-Aryl-N'-(4-pyridinyl)ureas is also proposed.

Heteroacyl Azides as Acylating Agents for Aromatic or Heteroatomic Amines (1)

The possibility of formation of substituted heterocyclic amides from heteroacyl azides and aromatic or heteroatomic amines was investigated.Although acylation proceeded in some cases under mild reaction conditions, formation of N,N'-disubstituted ureas was the main process at elevated temperatures.