132902-45-5Relevant academic research and scientific papers
ASYMMETRIC SYNTHESIS OF FURANONES
Desmaele, Didier,Angelo, Jean, d',Bois, Claudette
, p. 759 - 762 (1990)
Addition of imine 10 to methyl acrylate led exclusively, after hydrolytic work-up, to furanone 11 (95percent stereoselectivity).By contrast, addition of this imine to MVK was not regioselective, giving a mixture of compounds 18, 19 and 20.
New Approach to Chiral 5,5-Disubstituted Tetronic Acids. Enantioselective Synthesis of (-)-Vertinolide.
Desmaele, Didier
, p. 2925 - 2934 (1992)
A general protocol for enantioselective construction of tetronic acids bearing a stereogenic center at C-5 is described.The readily available Michael adduct 12, obtained by addition of methyl acrylate to imine 10 derived from 2-methyl-4,5-dihydrofuran-3-o
