132902-63-7Relevant academic research and scientific papers
Amphiphile self-assembly dynamics at the solution-solid interface reveal asymmetry in head/tail desorption
Castillo, Henry D.,Espinosa-Duran, John M.,Dobscha, James R.,Ashley, Daniel C.,Debnath, Sibali,Hirsch, Brandon E.,Schrecke, Samantha R.,Baik, Mu-Hyun,Ortoleva, Peter J.,Raghavachari, Krishnan,Flood, Amar H.,Tait, Steven L.
, p. 10076 - 10079 (2018)
Amphiphilic alkoxybenzonitriles (ABNs) of varying chain length are studied at the solution/graphite interface to analyze dynamics of assembly. Competitive self-assembly between ABNs and alkanoic acid solvent is shown by scanning tunneling microscopy (STM)
Highly symmetric 2D rhombic nanoporous networks arising from low symmetry amphiphiles
Ahn, Seokhoon,Morrison, Christine N.,Matzger, Adam J.
supporting information; experimental part, p. 7946 - 7947 (2009/12/02)
(Figure Presented) Highly symmetric 2D nanoporous molecular networks containing rhombic voids are demonstrated to be accessible from low symmetry amphiphilic molecules. The amide amphiphiles overcome the barrier to symmetry generation in the two-dimensional crystal through forming an aggregate as a building block. This aggregate consists of three inequivalent amphiphiles that assemble to create 3- and 6-fold rotation axes through hydrogen bonding. In the 6-fold rotation axis, an unusual hydrogen bonding network, supported by high resolution scanning tunneling microscopy(STM) images and computation, is observed. This network formed by amide groups significantly contributes to constructing the rhombic nanoporous network, whereas carboxylic acid amphiphiles do not adopt this nanoporo us network due to a geometric difference of hydrogen bonding. This investigation demonstrates that a high symmetry pattern is achievable withoutcorrelation with molecular symmetry through the proper combination of n oncovalent interactions of simple amphiphilic molecules.
4-Alkoxybenzamidines as new potent phospholipase A2 inhibitors
Aitdafoun, Mina,Mounier, Carine,Heymans, Francoise,Binisti, Carine,Cassian, Bon,Godfroid, Jean-Jacques
, p. 737 - 742 (2007/10/03)
A series of 4-alkoxybenzamidines was synthesized, varying the number of carbons of the alkyl chain, and their potency as phospholipase A2 (PLA2) inhibitors was evaluated. The relationship between their capacity to inhibit PLA2 activity and their lipophilicity was examined. The optimum of the inhibitory effect against two extracellular PLA2s from rabbit platelets and bovine pancreas was observed with compounds bearing an alkyl chain of 12 and 14 carbons. These 4-dodecyl and tetradecyloxybenzamidines inhibited bovine pancreatic and rabbit platelet lysate PLA2s with IC50 values of 3 μM and 5-5.8 μM, respectively. The mechanism of inhibition was of the competitive type. In addition, 4-tetradecyloxybenzamidine was shown to exert an anti-inflammatory effect in vivo on the carrageenan-induced rat paw oedema. These results show that 4-tetradecyloxybenzamidine will serve as an interesting tool to investigate the physiological role of mammalian-secreted PLA2, both in vitro and in vivo.
The preparation of novel ruthenium complexes for use in Langmuir-Blodgett films
Davies, Stephen G.,Smallridge, Andrew J.,Colbrook, Richard,Richardson, Tim,Roberts, Gareth G.
, p. 181 - 186 (2007/10/02)
A range of cationic cyclopentadienyl bisphosphine ruthenium nitrile complexes 5-C5H5)L2RuNC-Aryl>+ (L = phosphine or phosphite) have been prepared and characterised for use with the Langmuir-Blodgett deposition technique.
