1329422-25-4Relevant academic research and scientific papers
Pd-Catalyzed coupling of benzyl bromides with BMIDA-substituted: N -tosylhydrazones: synthesis of trans -alkenyl MIDA boronates
Li, Muyao,Li, Shichao,Li, Shu-Sen,Wang, Jianbo
, p. 399 - 402 (2022/01/19)
A palladium-catalyzed stereoselective synthesis of alkenyl boronates from N-methyliminodiacetyl boronate (BMIDA)-substituted N-tosylhydrazone and benzyl bromides is developed. A range of trans-alkenyl MIDA boronates as single stereoisomers were obtained in moderate yields with good functional group compatibility. The resultant boronate products may be transformed to other boron-containing compounds and may also be directly used in cross-coupling reactions.
Access to Cyclic Amino Boronates via Rhodium-Catalyzed Functionalization of Alkyl MIDA Boronates
St. Denis, Jeffrey D.,Lee, C. Frank,Yudin, Andrei K.
, p. 5764 - 5767 (2015/12/11)
Herein, we describe the rhodium-catalyzed C-H amination reaction of 1,2-boryl sulfamate esters derived from amphoteric α-boryl aldehydes. Depending on the substitution pattern of the boryl sulfamate ester, a diverse range of five- or six-membered ring heterocycles are accessible using this transformation. The highly chemoselective nature of the C-H functionalization reaction preserves the alkyl boronate functional group, which enables the synthesis of B-C-N and B-C-C-N motifs that are present in a number of hydrolase inhibitors.
