132958-66-8

Basic information

• Product Name: 4-Chlorothreonine
• Synonyms: 4-Chlorothreonine
• CAS NO: 132958-66-8
• Molecular Formula: C4H8ClNO3
• Molecular Weight: 153.56422
• Mol File: 132958-66-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 389.1°C at 760 mmHg
• Flash Point: 189.1°C
• Appearance: /
• Density: 1.498g/cm³
• Vapor Pressure: 1.15E-07mmHg at 25°C
• Refractive Index: 1.536
• CAS DataBase Reference: 4-Chlorothreonine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chlorothreonine(132958-66-8)
• EPA Substance Registry System: 4-Chlorothreonine(132958-66-8)

Safety Data

• Hazardous Substances Data: 132958-66-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C4H8ClNO3/c5-1-2(7)3(6)4(8)9/h2-3,7H,1,6H2,(H,8,9)

Upstream product

• 107-20-0 2-chloroethanal 
• 56-40-6 glycine 
• 142698-78-0 methyl (2S,3S)-2-<(benzyloxy)carbonylamino>-4-chloro-3-hydroxybutanoate 

Relevant articles and documents

Synthesis of γ-halogenated and long-chain β-hydroxy-α-amino acids and 2-amino-1,3-diols using threonine aldolases

The l- and d-threonine aldolase catalyzed formation of γ-halogenated and long-chain l- and d-3-alkylserine-derivatives 1-12, respectively, was shown starting from glycine and halogenated C2- or C4-C12 aldehydes. lTA from Pseudomonas putida accepted all tested aldehydes with strongly varying diastereoselectivity (de up to 93%). Only aldehydes smaller than decanal were converted by dTA from Alcaligenes xylosoxidans with good selectivities (de up to 73%). Utilizing isobutanal enantio- and diastereopure d-syn-2-amino-3-hydroxy-4-methylpentanoic acid was obtained (ee>99%, de>95%), which was converted to the corresponding 2-amino-1,3-diol.

Structure and Stereochemistry of Three Phytotoxins, Syringomycin, Syringotoxin and Syringostatin, Produced by Pseudomonas syringae pv. syringae

The structures of two phytotoxins, syringomycin and syringotoxin, produced by Pseudomonas syringae pv. syringae, were determined.Several amino acid residues of syringomycin were different from those in the syringostatins.Syringotoxin B proved to be syringostatin A.The three kinds of phytotoxins showed close structural similarity, and the stereochemistry of their components was deduced and compared.