132959-50-3

Upstream product

• 133007-27-9 (3R,7aS)-3-phenyl-2,3,5,6,7,7a-hexahydropyrrolo[2,1-b]oxazol-5-one 
• 762-72-1 allyl-trimethyl-silane 
• 56613-80-0 D-2-phenylglycinol 
• 158271-95-5 1-(2-hydroxy-1-phenylethyl)-1,5-dihydropyrrol-2-one 
• 241466-60-4 (R)-(+)-N-(1-phenyl-2-hydroxyethyl)succinimide 

Downstream Products

• 132959-52-5 (R)-1-((R)-2-Hydroxy-1-phenyl-ethyl)-5-propyl-pyrrolidin-2-one 
• 132959-51-4 (S)-5-Allyl-1-((R)-1-phenyl-2-phenylsulfanyl-ethyl)-pyrrolidin-2-one 
• 82259-09-4 (5S)-(+)-5-(1-Prop-2-enyl)-2-pyrrolidinone 
• 143771-09-9 (R)-2-(4-Oxo-heptyl)-pyrrolidine-1-carboxylic acid benzyl ester 
• 197229-64-4 (S)-benzyl 2-allylpyrrolidine-1-carboxylate 
• 386750-55-6 (R)-1-benzyloxycarbonyl-2-(4-oxo-decyl)pyrrolidine 
• 132959-48-9 (-)-N-<2-(1-Hydroxy-2(R)-phenylethyl)>-5(R)-propyl-2-pyrrolidine 

Relevant academic research and scientific papers

Expedient syntheses of indolizidines (-)-167B and (-)-209D

Indolizidine alkaloids (-)-167B and (-)-209D were synthesized via an expedient route using hydroacylation and amination.

Asymmetric synthesis of 5-substituted pyrrolidinones via a chiral N-acyliminium equivalent

5-Substituted pyrrolidinones 5 were synthesized in good yields and with fair to good diastereoselectivities from the chiral non-racemic oxazolopyrrolidinone 4. Various nucleophiles including cuprates, silanes and phosphites were used. The chiral induction