1329602-81-4

Basic information

• Product Name: N-[(1S,2R)-2-(D-(N'-acetyl)phenylalanyl)cyclohexanecarboxy]-α-L-fucopyranosylamine
• Synonyms: N-[(1S,2R)-2-(D-(N'-acetyl)phenylalanyl)cyclohexanecarboxy]-α-L-fucopyranosylamine
• CAS NO: 1329602-81-4
• Molecular Weight: 477.558
• Mol File: 1329602-81-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[(1S,2R)-2-(D-(N'-acetyl)phenylalanyl)cyclohexanecarboxy]-α-L-fucopyranosylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(1S,2R)-2-(D-(N'-acetyl)phenylalanyl)cyclohexanecarboxy]-α-L-fucopyranosylamine(1329602-81-4)
• EPA Substance Registry System: N-[(1S,2R)-2-(D-(N'-acetyl)phenylalanyl)cyclohexanecarboxy]-α-L-fucopyranosylamine(1329602-81-4)

Safety Data

• Hazardous Substances Data: 1329602-81-4(Hazardous Substances Data)

Upstream product

• 1329602-52-9 C₃₀H₄₁N₃O₁₀ 
• 10172-89-1 (R)-N-acetylphenylalanin 

Relevant articles and documents

Second generation of fucose-based DC-SIGN ligands: Affinity improvement and specificity versus Langerin

DC-SIGN and Langerin are two C-type lectins involved in the initial steps of HIV infections: the former acts as a viral attachment factor and facilitates viral invasion of the immune system, the latter has a protective effect. Potential antiviral compounds targeted against DC-SIGN were synthesized using a common fucosylamide anchor. Their DC-SIGN affinity was tested by SPR and found to be similar to that of the natural ligand Lewis-X (LeX). The compounds were also found to be selective for DC-SIGN and to interact only weakly with Langerin. These molecules are potentially useful therapeutic tools against sexually transmitted HIV infection.