132972-13-5Relevant academic research and scientific papers
Synthesis, in vitro antigiardial activity, SAR analysis and docking study of substituted chalcones
Cáceres-Castillo, David,Carballo, Rubén M.,Graniel-Sabido, Manlio,Mena-Rejón, Gonzalo J.,Mirón-López, Gumersindo,Moo-Puc, Rosa E.,Quijano-Qui?ones, Ramiro
, (2019)
A series of 15 chalcones-bearing substituents at positions 2, 4, and 5 of rings A and B were synthesized using microwave-assisted Claissen–Smichdt condensation and evaluated for their activity against Giardia lamblia and Green monkey kidney cells. Five co
On the stereochemistry of the olefinic double bond in 13-membered heterocyclic rings accessible by ring-closing metathesis reaction
Rao, H. Surya Prakash,Rafi, Shaik,Ratish Kumar,Guravaiah,Muthanna, Nandurka
supporting information, p. 6877 - 6880 (2013/01/15)
13-Membered heterocyclic ring analogs of the core structure of manzamine alkaloids were synthesized by ring closing metathesis (RCM) reaction. The influence of a remote heteroatom (N, O, S) on E/Z stereochemistry of the olefinic double bond formed in RCM reaction using Grubbs 1st and 2nd generation ruthenium carbene complexes was evaluated. Studies show that RCM reaction is kinetically controlled and the hetero atoms influence the double bond stereochemistry.
